PDBsum entry 8frd

Hydrolase

PDB id: 8frd

Contents

Protein chains

369 a.a.

Ligands

NAG-NAG ×5

Metals

_MG ×2

Waters ×738

PDB id:

8frd

Name:

Hydrolase

Title:

Mouse acidic mammalian chitinase, catalytic domain in complex with n, n'-diacetylchitobiose at ph 5.25

Structure:

Acidic mammalian chitinase. Chain: a, b. Synonym: amcase,ynl. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: chia, chia1. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: expicho-s.

Resolution:

1.68Å R-factor: 0.141 R-free: 0.168

Authors:

R.E.Diaz,J.S.Fraser

Key ref:

R.E.Diaz and j.s.fraser Structural characterization of ligand binding and ph-Specific enzymatic activity of mouse acidic mammal chitinase. To be published, . PubMed id: 37398339

Date:

06-Jan-23 Release date: 15-Mar-23

Protein chains

Q91XA9  (CHIA_MOUSE) -  Acidic mammalian chitinase from Mus musculus

Seq: 473 a.a.

Struc: 369 a.a.

Enzyme reactions

• Enzyme class: E.C.3.2.1.14 - chitinase.
• Reaction: Hydrolysis of the 1,4-beta-linkages of N-acetyl-D-glucosamine polymers of chitin.