PDBsum entry 8evc

Membrane protein

PDB id: 8evc

Contents

Protein chains

446 a.a.

441 a.a.

Ligands

NAG ×3

PCG ×4

PDB id:

8evc

Name:

Membrane protein

Title:

Cryo-em structure of cgmp bound truncated human cnga3/cngb3 channel in lipid nanodisc, open state

Structure:

Cyclic nucleotide-gated cation channel alpha-3. Chain: a, b, c. Synonym: cone photoreceptor cgmp-gated channel subunit alpha,cyclic nucleotide-gated channel alpha-3,cng channel alpha-3,cng-3,cng3. Engineered: yes. Cyclic nucleotide-gated cation channel beta-3. Chain: d. Synonym: cone photoreceptor cgmp-gated channel subunit beta,cyclic nucleotide-gated cation channel modulatory subunit,cyclic nucleotide-

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: cnga3, cncg3. Expressed in: homo sapiens. Expression_system_taxid: 9606. Gene: cngb3. Expression_system_taxid: 9606

Authors:

Z.Hu,J.Yang

Key ref:

Z.Hu et al. (2023). Conformational trajectory of allosteric gating of the cone photoreceptor cyclic nucleotide-Gated channel.. Nat commun, 14, 4284. PubMed id: 37463923

Date:

20-Oct-22 Release date: 09-Aug-23

Protein chains

Q16281  (CNGA3_HUMAN) -  Cyclic nucleotide-gated channel alpha-3 from Homo sapiens

Seq: 694 a.a.

Struc: 446 a.a.

Protein chain

Q9NQW8  (CNGB3_HUMAN) -  Cyclic nucleotide-gated channel beta-3 from Homo sapiens

Seq: 809 a.a.

Struc: 441 a.a.