PDBsum entry 8emk

Immune system

PDB id: 8emk

Contents

Protein chains

276 a.a.

99 a.a.

Ligands

LEU-PRO-PHE-ASP-LYS-PRO-THR-ILE-MET

Metals

_NA ×2

Waters ×416

PDB id:

8emk

Name:

Immune system

Title:

Crystal structure of hla-b 35:01-Np3 epitope from 1957 h2n2 influenza strain

Structure:

Mhc class i antigen. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Fragment: unp residues 21-119. Engineered: yes. Nucleoprotein np3 epitope. Chain: c.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Influenza a virus (strain a/singapore/1/1957

Resolution:

1.67Å R-factor: 0.180 R-free: 0.206

Authors:

D.R.Littler,J.Rossjohn

Key ref:

S.M.Quinones-Parra et al. Molecular determinants of cross-Strain influenza a VI recognition by t-Cell receptors. To be published, .

Date:

27-Sep-22 Release date: 27-Mar-24

Protein chain

F4NBT2  (F4NBT2_HUMAN) -  MHC class I antigen (Fragment) from Homo sapiens

Seq: 337 a.a.

Struc: 276 a.a.

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 99 a.a.