PDBsum entry 8efi

Motor protein

PDB id: 8efi

Contents

Protein chains

742 a.a.

371 a.a.

166 a.a.

Ligands

ADP ×5

Metals

_MG ×5

PDB id:

8efi

Name:

Motor protein

Title:

Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in the rigor form

Structure:

Myosin-7. Chain: m. Synonym: myosin heavy chain 7,myosin heavy chain slow isoform,myhc- slow,myosin heavy chain,cardiac muscle beta isoform,myhc-beta. Engineered: yes. Actin, alpha cardiac muscle 1. Chain: b, c, d, e, f. Synonym: cardiac muscle alpha actin 1. Tropomyosin alpha-1 chain.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: myh7, myhcb. Expressed in: mus musculus. Expression_system_taxid: 10090. Sus scrofa. Pig. Organism_taxid: 9823.

Authors:

M.H.Doran,W.Lehman,M.J.Rynkiewicz

Key ref:

M.H.Doran et al. (2023). Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation.. J gen physiol, 155, . PubMed id: 36459134

Date:

08-Sep-22 Release date: 23-Nov-22

Protein chain

P12883  (MYH7_HUMAN) -  Myosin-7 from Homo sapiens

Seq: 1935 a.a.

Struc: 742 a.a.

Protein chains

B6VNT8  (B6VNT8_PIG) -  Actin, alpha cardiac muscle 1 from Sus scrofa

Seq: 377 a.a.

Struc: 371 a.a.

Protein chains

P09493  (TPM1_HUMAN) -  Tropomyosin alpha-1 chain from Homo sapiens

Seq: 284 a.a.

Struc: 166 a.a.