PDBsum entry 8e4c

Immune system

PDB id: 8e4c

Contents

Protein chains

253 a.a.

142 a.a.

157 a.a.

Ligands

NAG ×5

PDB id:

8e4c

Name:

Immune system

Title:

Igm bcr fab truncated form

Structure:

Isoform 2 of immunoglobulin heavy constant mu. Chain: b, a. Engineered: yes. Other_details: b1-8 leader sequence: mgwsciilflvatatgvhs strep tag: wshpqfek rigid linker: aeaaakeaaakeaaaka. B-cell antigen receptor complex-associated protein alpha chain,yellow fluorescent protein. Chain: c. Synonym: ig-alpha,mb-1 membrane glycoprotein,membrane-bound

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: ighm, igh-6. Expressed in: mus musculus. Expression_system_taxid: 10090. Gene: cd79a, iga, mb-1, luxy. Gene: cd79b, igb. Expression_system_taxid: 10090

Authors:

Y.Dong,X.Pi,H.Wu,M.Reth

Key ref:

Y.Dong et al. (2022). Structural principles of b cell antigen receptor asse. Nature, 612, 156. PubMed id: 36228656

Date:

18-Aug-22 Release date: 16-Nov-22

Protein chains

P01872  (IGHM_MOUSE) -  Immunoglobulin heavy constant mu from Mus musculus

Seq: 454 a.a.

Struc: 253 a.a.*

Protein chain

P11911  (CD79A_MOUSE) -  B-cell antigen receptor complex-associated protein alpha chain from Mus musculus

Seq: 220 a.a.

Struc: 142 a.a.

Protein chain

P21578  (LUXY_ALIFS) -  Yellow fluorescent protein from Aliivibrio fischeri

Seq: 194 a.a.

Struc: 142 a.a.*

Protein chain

P15530  (CD79B_MOUSE) -  B-cell antigen receptor complex-associated protein beta chain from Mus musculus

Seq: 228 a.a.

Struc: 157 a.a.

* PDB and UniProt seqs differ at 150 residue positions (black crosses)