PDBsum entry 8dv4

Immune system

PDB id: 8dv4

Contents

Protein chains

273 a.a.

98 a.a.

189 a.a.

244 a.a.

Ligands

NAG-NAG-BMA

NAG-NAG-BMA-MAN

EDO ×6

GOL ×2

MAN

NAG

CUY

PIE

Metals

_NA ×3

_CL ×3

Waters ×247

PDB id:

8dv4

Name:

Immune system

Title:

Crystal structure of the bc8b tcr-cd1b-pi complex

Structure:

T-cell surface glycoprotein cd1b. Chain: a. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. T-cell receptor alpha variable trav9-2. Chain: d. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: cd1b. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek392s. Gene: b2m, cdabp0092, hdcma22p. Expression_system_cell_line: hek293s.

Resolution:

2.40Å R-factor: 0.195 R-free: 0.255

Authors:

R.Farquhar,J.Rossjohn,A.Shahine

Key ref:

R.Farquhar et al. (2023). Alpha beta t-Cell receptor recognition of self-Phosphatidylinositol presented by cd1b.. J biol chem, 299, 02849. PubMed id: 36587766

Date:

28-Jul-22 Release date: 19-Apr-23

Protein chain

P29016  (CD1B_HUMAN) -  T-cell surface glycoprotein CD1b from Homo sapiens

Seq: 333 a.a.

Struc: 273 a.a.

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 98 a.a.

Protein chain

No UniProt id for this chain

Struc: 189 a.a.

Protein chain

No UniProt id for this chain

Struc: 244 a.a.