PDBsum entry 8d5c

Viral protein/immune system

PDB id: 8d5c

Contents

Protein chains

129 a.a.

377 a.a.

176 a.a.

122 a.a.

113 a.a.

104 a.a.

PDB id:

8d5c

Name:

Viral protein/immune system

Title:

Anti-HIV-1 gp120-scd4 complex antibody cg10 fab in complex with b41- scd4

Structure:

Envelope glycoprotein gp41. Chain: x, y, z. Engineered: yes. Envelope glycoprotein gp160. Chain: a, b, c. Synonym: env polyprotein. Engineered: yes. T-cell surface glycoprotein cd4. Chain: d, e, f.

Source:

Human immunodeficiency virus 1. Organism_taxid: 11676. Strain: b41. Gene: env. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: cho flp-in (invitrogen). Human immunodeficiency virus. Organism_taxid: 12721.

Authors:

Z.Yang,P.J.Bjorkman,J.M.Gershoni

Key ref:

Z.Yang et al. (2022). Antibody recognition of cd4-Induced open HIV-1 env tr. J.Virol., 96, 08222. PubMed id: 36448805 DOI: 10.1128/JVI.01082-22

Date:

04-Jun-22 Release date: 16-Nov-22

Protein chains

B3UES2  (B3UES2_9HIV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus 1

Seq: 860 a.a.

Struc: 129 a.a.*

Protein chains

B3UES2  (B3UES2_9HIV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus 1

Seq: 860 a.a.

Struc: 377 a.a.*

Protein chains

P01730  (CD4_HUMAN) -  T-cell surface glycoprotein CD4 from Homo sapiens

Seq: 458 a.a.

Struc: 176 a.a.

Protein chains

No UniProt id for this chain

Struc: 122 a.a.

Protein chains

No UniProt id for this chain

Struc: 113 a.a.

Protein chain

No UniProt id for this chain

Struc: 104 a.a.

* PDB and UniProt seqs differ at 2 residue positions (black crosses)