PDBsum entry 8cpm

Metal binding protein

PDB id: 8cpm

Contents

Protein chains

(+ 18 more) 173 a.a.

Metals

_MG ×14

_NA ×24

Waters ×1972

PDB id:

8cpm

Name:

Metal binding protein

Title:

Human apoferritin after 405 nm laser exposure

Structure:

Ferritin heavy chain, n-terminally processed. Chain: 1, 2, 4, 6, a, b, e, f, g, h, i, k, m, o, p, q, s, u, w, x, y, a, e, r. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fth1, fth, fthl6, ok/sw-cl.84, pig15. Expressed in: escherichia coli. Expression_system_taxid: 562

Authors:

M.G.F.Last,W.E.M.Noteborn,T.H.Sharp

Key ref:

M.G.F.Last et al. Super-Resolution fluorescence imaging of cryosamples not damage protein structure. To be published, . PubMed id: 37918761

Date:

03-Mar-23 Release date: 15-Mar-23

Protein chains

P02794  (FRIH_HUMAN) -  Ferritin heavy chain from Homo sapiens

Seq: 183 a.a.

Struc: 173 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.1.16.3.1 - ferroxidase.
• Reaction: 4 Fe²⁺ + O2 + 4 H⁺ = 4 Fe³⁺ + 2 H2O
• Cofactor: Cu cation

Molecule diagrams generated from .mol files obtained from the KEGG ftp site