spacer
spacer

PDBsum entry 8cmu
Go to PDB code: 
protein Protein-protein interface(s) links
Blood clotting PDB id
8cmu

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
722 a.a.
125 a.a.
Waters ×748
PDB id:
8cmu
Name: Blood clotting
Title: High resolution structure of the coagulation factor xiii a2b2 heterotetramer complex.
Structure: Coagulation factor xiii a chain. Chain: a, b. Synonym: coagulation factor xiiia,protein-glutamine gamma- glutamyltransferase a chain,transglutaminase a chain. Coagulation factor xiii b chain. Chain: c, d. Synonym: fibrin-stabilizing factor b subunit,protein-glutamine gamma- glutamyltransferase b chain,transglutaminase b chain
Source: Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
Authors: S.Singh,D.Urgular,G.Hagelueken,M.Geyer,A.Biswas
Key ref: S.Singh et al. The cryo-Em structure of the plasma coagulation facto complex at 2.68 angstrom resolution.. To be published, . PubMed id: 39447073
Date:
21-Feb-23     Release date:   11-Sep-24    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P00488  (F13A_HUMAN) -  Coagulation factor XIII A chain from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		732 a.a.
722 a.a.
Protein chains
Pfam   ArchSchema ?
P05160  (F13B_HUMAN) -  Coagulation factor XIII B chain from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		661 a.a.
125 a.a.
Key:    PfamA domain  Secondary structure

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.2.3.2.13  - protein-glutamine gamma-glutamyltransferase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N6-5- L-glutamyl-[protein] + NH4+
protein-L-glutamine
 + protein-L-lysine
 = protein with an N(6)- (gamma-glutamyl)-L-lysine cross-link
 + NH(3)
      Cofactor: Ca(2+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 

spacer
spacer