PDBsum entry 8c1c

Immune system

PDB id: 8c1c

Contents

Protein chains

426 a.a.

107 a.a.

171 a.a.

Ligands

NAG-NAG-BMA-MAN-MAN ×2

NAG-NAG-MAN-MAN-MAN ×2

NAG-NAG ×3

NAG ×2

PDB id:

8c1c

Name:

Immune system

Title:

Structure of ige bound to the ectodomain of fceria

Structure:

Immunoglobulin heavy constant epsilon. Chain: h, x. Synonym: ig epsilon chain c region,ig epsilon chain c region nd. Engineered: yes. Immunoglobulin kappa constant. Chain: l, y. Synonym: ig kappa chain c region,ig kappa chain c region ag,ig kappa chain c region cum,ig kappa chain c region eu,ig kappa chain c region ou,ig kappa chain c region roy,ig kappa chain c region ti.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ighe. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293. Gene: igkc. Gene: fcer1a, fce1a.

Authors:

G.R.Andersen,R.K.Jensen

Key ref:

G.R.Andersen and r.k.jensen Structure of ige bound to the ectodomain of fceria. To be published, .

Date:

20-Dec-22 Release date: 29-Mar-23

Protein chains

P01854  (IGHE_HUMAN) -  Immunoglobulin heavy constant epsilon from Homo sapiens

Seq: 546 a.a.

Struc: 426 a.a.*

Protein chains

P01834  (IGKC_HUMAN) -  Immunoglobulin kappa constant from Homo sapiens

Seq: 107 a.a.

Struc: 107 a.a.*

Protein chain

P12319  (FCERA_HUMAN) -  High affinity immunoglobulin epsilon receptor subunit alpha from Homo sapiens

Seq: 257 a.a.

Struc: 171 a.a.

* PDB and UniProt seqs differ at 4 residue positions (black crosses)