PDBsum entry 7zoz

Immune system

PDB id: 7zoz

Contents

Protein chains

125 a.a.

223 a.a.

213 a.a.

Waters ×305

PDB id:

7zoz

Name:

Immune system

Title:

Crystal structure of siglec-15 in complex with fab

Structure:

Sialic acid-binding ig-like lectin 15. Chain: a. Synonym: siglec-15,cd33 antigen-like 3. Engineered: yes. Anti-siglec 15 fab hc. Chain: h. Engineered: yes. Anti-siglec 15 fab lc. Chain: l.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: siglec15, cd33l3. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_taxid: 9606

Resolution:

2.10Å R-factor: 0.178 R-free: 0.218

Authors:

M.P.Lenza,I.Oyenarte,J.Jimenez-Barbero,J.Ereno-Orbea

Key ref:

M.P.Lenza et al. (2023). Structural insights into siglec-15 reveal glycosylati dependency for its interaction with t cells through i cd11b.. Nat commun, 14, 3496. PubMed id: 37311743

Date:

26-Apr-22 Release date: 28-Jun-23

Protein chain

Q6ZMC9  (SIG15_HUMAN) -  Sialic acid-binding Ig-like lectin 15 from Homo sapiens

Seq: 328 a.a.

Struc: 125 a.a.

Protein chain

No UniProt id for this chain

Struc: 223 a.a.

Protein chain

No UniProt id for this chain

Struc: 213 a.a.