Aal160 fab in complex with human interleukin-1 beta
Structure:
Aal160 fab heavy-chain. Chain: h. Engineered: yes. Interleukin-1 beta. Chain: i. Fragment: fab light-chain. Synonym: il-1 beta,catabolin. Engineered: yes. Other_details: mature form.
Source:
Homo sapiens. Organism_taxid: 9606. Expressed in: homo sapiens x mus musculus hybrid cell line. Expression_system_taxid: 1131344. Human. Gene: il1b, il1f2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: t1.
Resolution:
3.30Å
R-factor:
0.241
R-free:
0.269
Authors:
J.M.Rondeau,S.Lehmann
Key ref:
I.Levin
et al.
Utilizing the intrinsic plasticity of antibodies - Retargeting an anti-Il-1b antibody into a functional anti-Il-17a by computational design.
To be published,
.
PubMed id: 37773269
Links
