PDBsum entry 7x2a

Viral protein

PDB id: 7x2a

Contents

Protein chains

1159 a.a.

947 a.a.

221 a.a.

212 a.a.

PDB id:

7x2a

Name:

Viral protein

Title:

Mers-cov spike complex with s41 neutralizing antibody fab class1 (1u2d rbd with 1fab)

Structure:

Mers-cov spike glycoprotein. Chain: a, b, c. Synonym: s glycoprotein,e2,peplomer protein. Engineered: yes. Mutation: yes. Antibody s41 heavy chain. Chain: h. Engineered: yes. Antibody s41 light chain.

Source:

Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens.

Authors:

J.W.Zeng,S.Y.Zhang,H.X.Zhou,X.W.Wang

Key ref:

S.Zhang et al. (2022). Cryoelectron microscopy structures of a human neutral antibody bound to mers-Cov spike glycoprotein.. Front microbiol, 13, 88298. PubMed id: 36246239

Date:

25-Feb-22 Release date: 09-Nov-22

Protein chain

K9N5Q8  (SPIKE_CVEMC) -  Spike glycoprotein from Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)

Seq: 1353 a.a.

Struc: 1159 a.a.*

Protein chains

K9N5Q8  (SPIKE_CVEMC) -  Spike glycoprotein from Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)

Seq: 1353 a.a.

Struc: 947 a.a.*

Protein chain

No UniProt id for this chain

Struc: 221 a.a.

Protein chain

No UniProt id for this chain

Struc: 212 a.a.

* PDB and UniProt seqs differ at 7 residue positions (black crosses)