PDBsum entry 7vwc

Transport protein

PDB id: 7vwc

Contents

Protein chains

617 a.a.

Ligands

82T ×2

PDB id:

7vwc

Name:

Transport protein

Title:

Cryo-em structure of human very long-chain fatty acid abc transporter abcd1

Structure:

Peroxisomal membrane protein related,atp-binding cassette sub-family d member 1. Chain: a, b. Synonym: adrenoleukodystrophy protein,aldp. Engineered: yes

Source:

Caenorhabditis elegans, homo sapiens. Human. Organism_taxid: 6239, 9606. Gene: pmp-4, cele_t02d1.5, t02d1.5, abcd1, ald. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek 293f. Expression_system_tissue: kidney. Embryo.

Authors:

Z.P.Chen,D.Xu,L.Wang,Y.X.Mao,L.Yang,M.T.Cheng,W.T.Hou,Y.X.Chen, C.Z.Zhou

Key ref:

Z.P.Chen et al. Cryo-Em structure of human very long-Chain fatty acid transporter abcd1. To be published, . PubMed id: 35676282

Date:

10-Nov-21 Release date: 18-May-22

Protein chains

O45730  (O45730_CAEEL) -  ABC transporter domain-containing protein from Caenorhabditis elegans

Seq: 734 a.a.

Struc: 617 a.a.*

Protein chains

P33897  (ABCD1_HUMAN) -  ATP-binding cassette sub-family D member 1 from Homo sapiens

Seq: 745 a.a.

Struc: 617 a.a.

* PDB and UniProt seqs differ at 248 residue positions (black crosses)

Enzyme reactions

• Enzyme class 2: E.C.3.1.2.- - ?????
• Enzyme class 3: E.C.7.6.2.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.