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PDBsum entry 7uxt
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PDB id:
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Hydrolase
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Title:
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Crystal structure of ligand-free sethsa
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Structure:
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Usg protein. Chain: b, a. Synonym: sethsa. Engineered: yes
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Source:
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Streptococcus equi. Organism_taxid: 1336. Gene: gbl60_08830. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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3.40Å
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R-factor:
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0.238
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R-free:
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0.291
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Authors:
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Y.Shi,V.Masic,T.Mosaiab,J.D.Nanson,B.Kobe,T.Ve
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Key ref:
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m.k.manik
et al.
(2022).
Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Science,
0,
eadc8969.
PubMed id:
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Date:
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06-May-22
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Release date:
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07-Sep-22
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PROCHECK
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Headers
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References
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C0MAL8
(THSA_STRE4) -
NAD(+) hydrolase ThsA from Streptococcus equi subsp. equi (strain 4047)
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Seq:
Struc:
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473 a.a.
467 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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Enzyme class:
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E.C.3.2.2.5
- NAD(+) glycohydrolase.
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Reaction:
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NAD+ + H2O = ADP-D-ribose + nicotinamide + H+
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NAD(+)
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+
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H2O
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=
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ADP-D-ribose
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+
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nicotinamide
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Science
0:eadc8969
(2022)
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PubMed id:
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Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
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m.k.manik,
y.shi,
s.li,
m.a.zaydman,
n.damaraju,
s.eastmant.g.smith,
w.gu,
v.masic,
t.mosaiab,
j.s.weagley,
s.j.hance.vasquez,
l.hartley-tassell,
n.kargios,
n.maruta,
b.y.j.h.burdett,
m.j.landsberg,
m.a.schembri,
i.prokes,
l.song,
m.grant,
a.diantonio,
j.d.nanson,
m.guo,
j.milbrandt,
t.ve.
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ABSTRACT
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