PDBsum entry 7udc

Exocytosis

PDB id: 7udc

Contents

Protein chains

542 a.a.

215 a.a.

49 a.a.

PDB id:

7udc

Name:

Exocytosis

Title:

Cryo-em structures of a synaptobrevin-munc18-1-syntaxin-1 complex class1

Structure:

Syntaxin-binding protein 1. Chain: a. Synonym: n-sec1,protein unc-18 homolog 1,unc18-1,protein unc-18 homolog a,unc-18a,p67,rbsec1. Engineered: yes. Mutation: yes. Syntaxin-1a. Chain: b. Synonym: neuron-specific antigen hpc-1,synaptotagmin-associated 35

Source:

Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: stxbp1, unc18a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: stx1a, sap. Gene: vamp2, syb2. Expression_system_taxid: 469008

Authors:

J.Rizo,X.Bai,K.P.Stepien,J.Xu,X.Zhang

Key ref:

K.P.Stepien et al. Snare assembly enlightened by cryo-Em structures of a synaptobrevin-Munc18-1-Syntaxin-1 complex. To be published, . PubMed id: 35731863

Date:

18-Mar-22 Release date: 06-Apr-22

Protein chain

P61765  (STXB1_RAT) -  Syntaxin-binding protein 1 from Rattus norvegicus

Seq: 594 a.a.

Struc: 542 a.a.

Protein chain

P32851  (STX1A_RAT) -  Syntaxin-1A from Rattus norvegicus

Seq: 288 a.a.

Struc: 215 a.a.*

Protein chain

P63027  (VAMP2_HUMAN) -  Vesicle-associated membrane protein 2 from Homo sapiens

Seq: 116 a.a.

Struc: 49 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)