PDBsum entry 7st8

Immune system

PDB id: 7st8

Contents

Protein chains

223 a.a.

217 a.a.

15 a.a.

Waters ×26

PDB id:

7st8

Name:

Immune system

Title:

Crystal structure of 7h2.2 fab in complex with sas1b c-terminal region

Structure:

7h2.2 fab heavy chain. Chain: h. Engineered: yes. 7h2.2 fab light chain. Chain: l. Engineered: yes. Astacin-like metalloendopeptidase. Chain: s. Fragment: c-terminus.

Source:

Mus musculus. Organism_taxid: 10090. Expressed in: mus musculus. Expression_system_taxid: 10090. Homo sapiens. Human. Organism_taxid: 9606. Gene: astl. Expressed in: escherichia coli.

Resolution:

2.75Å R-factor: 0.233 R-free: 0.270

Authors:

M.S.G.Legg,S.V.Evans

Key ref:

M.S.G.Legg et al. (2022). Monoclonal antibody 7h2.2 binds the c-Terminus of the cancer-Oocyte antigen sas1b through the hydrophilic f a conserved amphipathic helix corresponding to one of two regions predicted to be ordered. Acta crystallogr ,Sect d, 78, 623. PubMed id: 35503210

Date:

12-Nov-21 Release date: 11-May-22

Protein chain

No UniProt id for this chain

Struc: 223 a.a.

Protein chain

No UniProt id for this chain

Struc: 217 a.a.

Protein chain

Q6HA08  (ASTL_HUMAN) -  Astacin-like metalloendopeptidase from Homo sapiens

Seq: 431 a.a.

Struc: 15 a.a.

Enzyme reactions

• Enzyme class: Chain S: E.C.3.4.-.-