Crystal structure of sars-cov-2 spike stem helix peptide in complex with neutralizing antibody cc40.8
Structure:
Cc40.8 fab heavy chain. Chain: h. Engineered: yes. Cc40.8 fab light chain. Chain: l. Engineered: yes. Stem helix peptide of spike protein s2'. Chain: c. Engineered: yes
Source:
Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Synthetic: yes. Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2.
Resolution:
1.61Å
R-factor:
0.175
R-free:
0.206
Authors:
M.Yuan,I.A.Wilson
Key ref:
P.Zhou
et al.
A protective broadly cross-Reactive human antibody de conserved site of vulnerability on beta-Coronavirus s.
To be published,
.
PubMed id: 35133175
Date:
18-Oct-21
Release date:
12-Jan-22
PROCHECK
Headers
References
Protein chain
No UniProt id for this chain
Struc:
208 a.a.
Protein chain
No UniProt id for this chain
Struc:
211 a.a.
Protein chain
P0DTC2 (SPIKE_SARS2) -
Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2