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PDBsum entry 7s8f

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protein ligands Protein-protein interface(s) links
Immune system PDB id
7s8f

 

 

 

 

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Contents
Protein chains
275 a.a.
100 a.a.
Ligands
GLU-PRO-ARG-SER-
PRO-SER-HIS-SER-
MET
GOL ×5
Waters ×489
PDB id:
7s8f
Name: Immune system
Title: Structure of hla-b 07:02 In complex with mll(747-755) peptide and bound glycerol
Structure: Hla class i histocompatibility antigen, b-7 alpha chain. Chain: a. Fragment: unp residues 25-299. Synonym: mhc class i antigen b 7. Engineered: yes. Beta-2-microglobulin. Chain: b. Fragment: unp residues 21-119. Engineered: yes.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-b, hlab. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Organism_taxid: 9606
Resolution:
1.80Å     R-factor:   0.165     R-free:   0.206
Authors: Y.Patskovsky,S.Nyovanie,L.Patskovska,A.Natarajan,B.Joshi,B.Morin, C.Brittsan,O.Huber,S.Gordon,X.Michelet,F.Schmitzberger,R.Stein, M.Findeis,A.Hurwitz,M.Van Dijk,J.Buell,D.Underwood,M.Krogsgaard
Key ref: Y.Patskovsky et al. (2023). Molecular mechanism of phosphopeptide neoantigen immunogenicity.. Nat commun, 14, 3763. PubMed id: 37353482
Date:
17-Sep-21     Release date:   02-Nov-22    
PROCHECK
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 Headers
 References

Protein chain
P01889  (1B07_HUMAN) -  HLA class I histocompatibility antigen, B alpha chain from Homo sapiens
Seq:
Struc:
362 a.a.
275 a.a.
Protein chain
P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens
Seq:
Struc:
119 a.a.
100 a.a.*
Key:    Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

 

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