spacer
spacer

PDBsum entry 7s8c

Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Membrane protein PDB id
7s8c

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
612 a.a.
Ligands
ECL ×4
Y01 ×12
POV ×16
Metals
_CL
_CA
PDB id:
7s8c
Name: Membrane protein
Title: Cryo-em structure of human trpv6 in complex with inhibitor econazole
Structure: Transient receptor potential cation channel subfamily v member 6. Chain: a, b, c, d. Synonym: trpv6,cat-like,cat-l,calcium transport protein 1,cat1, epithelial calcium channel 2,ecac2. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: trpv6, ecac2. Expressed in: homo sapiens. Expression_system_taxid: 9606
Authors: A.Neuberger,K.D.Nadezhdin,A.I.Sobolevsky
Key ref: A.Neuberger et al. (2021). Structural mechanisms of trpv6 inhibition by rutheniu and econazole.. Nat commun, 12, 6284. PubMed id: 34725357
Date:
17-Sep-21     Release date:   17-Nov-21    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9H1D0  (TRPV6_HUMAN) -  Transient receptor potential cation channel subfamily V member 6 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
765 a.a.
612 a.a.
Key:    PfamA domain  Secondary structure

 

 

spacer

spacer