PDBsum entry 7qap

Membrane protein

PDB id: 7qap

Contents

Protein chain

35 a.a.

PDB id:

7qap

Name:

Membrane protein

Title:

Three-dimensional structure of the pgam5 g17l mutant tmd

Structure:

Serine/threonine-protein phosphatase pgam5, mitochondrial. Chain: a. Synonym: bcl-xl-binding protein v68,phosphoglycerate mutase family member 5. Engineered: yes

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606

NMR struc:

20 models

Authors:

M.Silber,C.Muhle-Goll

Key ref:

V.Siebert et al. Cleavage of pgam5 by the rhomboid intramembrane prote parl is governed by transmembrane helix dynamics and oligomeric state. To be published, . PubMed id: 35921890

Date:

17-Nov-21 Release date: 04-May-22

Protein chain

Q96HS1  (PGAM5_HUMAN) -  Serine/threonine-protein phosphatase PGAM5, mitochondrial from Homo sapiens

Seq: 289 a.a.

Struc: 35 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.1.3.16 - protein-serine/threonine phosphatase.
• Reaction:
  1. O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate
  2. O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site