PDBsum entry 7pc2

Viral protein

PDB id: 7pc2

Contents

Protein chains

130 a.a.

108 a.a.

445 a.a.

129 a.a.

121 a.a.

98 a.a.

Ligands

NAG-NAG ×19

NAG-NAG-BMA-MAN-MAN-MAN-MAN-MAN-MAN ×3

NAG-NAG-BMA-MAN-MAN-MAN-MAN-MAN ×5

NAG-NAG-BMA ×10

NAG-NAG-BMA-MAN-MAN-MAN-MAN-MAN-MAN-MAN-MAN ×3

NAG-NAG-BMA-MAN-MAN-MAN-MAN

NAG-NAG-BMA-MAN-MAN ×3

NAG ×20

PDB id:

7pc2

Name:

Viral protein

Title:

HIV-1 env (bg505 sosip.664) in complex with the iga bnab 7-269 and the antibody 3bnc117.

Structure:

7-269 iga fab heavy chain. Chain: o, m, q. Engineered: yes. 7-269 iga fab light chain. Chain: p, n, r. Engineered: yes. Gp120, bg505 sosip.664 t332n. Chain: a, b, c. Engineered: yes.

Source:

Homo sapiens. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Human immunodeficiency virus. Organism_taxid: 12721. Strain: bg505. Gene: env. Expression_system_taxid: 9606

Authors:

I.Fernandez,F.Bontems,G.Pehau-Arnaudet,F.Rey

Key ref:

v.lorin et al. (2022). Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller. J.Exp.Med., 219, . PubMed id: 35230385

Date:

03-Aug-21 Release date: 23-Feb-22

Protein chains

No UniProt id for this chain

Struc: 130 a.a.

Protein chains

No UniProt id for this chain

Struc: 108 a.a.

Protein chains

Q2N0S6  (Q2N0S6_HV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1

Seq: 860 a.a.

Struc: 445 a.a.*

Protein chains

Q2N0S6  (Q2N0S6_HV1) -  Envelope glycoprotein gp160 from Human immunodeficiency virus type 1

Seq: 860 a.a.

Struc: 129 a.a.*

Protein chains

No UniProt id for this chain

Struc: 121 a.a.

Protein chains

No UniProt id for this chain

Struc: 98 a.a.

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

J.Exp.Med. 219: (2022)

PubMed id: 35230385

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.

v.lorin, i.fernandez, f.a.rey, h.mouquet.

ABSTRACT

No abstract given.