PDBsum entry 7olh

Protein binding

PDB id: 7olh

Contents

Protein chains

(+ 0 more) 368 a.a.

(+ 0 more) 146 a.a.

PDB id:

7olh

Name:

Protein binding

Title:

Bacillus subtilis complex structure 1 of diadenylate cyclase cdaa cytoplasmic domain (cdaacd) and the phosphoglucomutase glmm short variant (glmmf369)

Structure:

Phosphoglucosamine mutase. Chain: a, b, c, d, e, f. Engineered: yes. Cyclic di-amp synthase cdaa. Chain: g, h, i, j, k, l. Synonym: c-di-amp synthase,diadenylate cyclase,dac. Engineered: yes

Source:

Bacillus subtilis (strain 168). Organism_taxid: 224308. Strain: 168. Gene: glmm, ybbt, bsu01770. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: cdaa, ybbp, bsu01750. Expression_system_taxid: 469008

Resolution:

3.65Å R-factor: 0.243 R-free: 0.262

Authors:

M.Pathania,A.G.Grundling,P.Freemont

Key ref:

M.Pathania et al. Complex structure of the bacillus subtilis cdaa c-Di- Cyclase domain and the phosphoglucomutase glmm. To be published, . PubMed id: 34678313

Date:

20-May-21 Release date: 27-Oct-21

Protein chains

O34824  (GLMM_BACSU) -  Phosphoglucosamine mutase from Bacillus subtilis (strain 168)

Seq: 448 a.a.

Struc: 368 a.a.

Protein chains

Q45589  (CDAA_BACSU) -  Cyclic di-AMP synthase CdaA from Bacillus subtilis (strain 168)

Seq: 273 a.a.

Struc: 146 a.a.

Enzyme reactions

• Enzyme class 1: Chains A, B, C, D, E, F: E.C.5.4.2.10 - phosphoglucosamine mutase.
• Pathway: UDP-N-acetylglucosamine Biosynthesis
• Reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate
• Enzyme class 2: Chains G, H, I, J, K, L: E.C.2.7.7.85 - diadenylate cyclase.
• Reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site