PDBsum entry 7odb

Chaperone

PDB id: 7odb

Contents

Protein chain

536 a.a.

Ligands

EPE

GOL ×3

V8Q

Metals

__K ×2

Waters ×444

PDB id:

7odb

Name:

Chaperone

Title:

Crystal structure of bovine hsc70(aa1-554)e213a/d214a in complex with triazine-derivative

Structure:

Heat shock cognate 71 kda protein. Chain: a. Synonym: heat shock 70 kda protein 8. Engineered: yes. Mutation: yes

Source:

Bos taurus. Bovine. Organism_taxid: 9913. Gene: hspa8, hsc70. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.66Å R-factor: 0.200 R-free: 0.208

Authors:

M.Zehe,C.Grimm,C.Sotriffer

Key ref:

M.Zehe et al. Combined in-Solution and crystallographic fragment sc on a two-Domain hsp70 construct. To be published, . PubMed id: 38317495

Date:

29-Apr-21 Release date: 01-Jun-22

Protein chain

P19120  (HSP7C_BOVIN) -  Heat shock cognate 71 kDa protein from Bos taurus

Seq: 650 a.a.

Struc: 536 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.6.4.10 - non-chaperonin molecular chaperone ATPase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site