PDBsum entry 7ocm

De novo protein

PDB id: 7ocm

Contents

Protein chain

174 a.a.

Ligands

EPE ×2

Waters ×122

PDB id:

7ocm

Name:

De novo protein

Title:

K1k1h6, a potent recombinant minimal hepatocyte growth factor/scatter factor mimic

Structure:

Hepatocyte growth factor alpha chain,hepatocyte growth factor alpha chain. Chain: a. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hgf, hpta. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.70Å R-factor: 0.165 R-free: 0.195

Authors:

H.De Jonge,G.De Nola,E.Gherardi

Key ref:

G.De nola et al. (2022). Dimerization of kringle 1 domain from hepatocyte grow factor/scatter factor provides a potent met receptor agonist.. Life sci alliance, 5, . PubMed id: 35905995

Date:

27-Apr-21 Release date: 07-Jul-21

Protein chain

P14210  (HGF_HUMAN) -  Hepatocyte growth factor from Homo sapiens

Seq: 728 a.a.

Struc: 174 a.a.*

* PDB and UniProt seqs differ at 53 residue positions (black crosses)