PDBsum entry 7obc

Signaling protein

PDB id: 7obc

Contents

Protein chain

236 a.a.

Ligands

LYS-ASP-LYS-ALA-LYS-SEP-CYS

FAR

Metals

_MG

_CL

Waters ×447

PDB id:

7obc

Name:

Signaling protein

Title:

Crystal structure of 14-3-3 sigma in complex with phosphorylated and farnesylated rnd3 peptide

Structure:

14-3-3 protein sigma. Chain: a. Synonym: epithelial cell marker protein 1,stratifin. Engineered: yes. Rho-related gtp-binding protein rhoe. Chain: b. Synonym: protein memb,rho family gtpase 3,rho-related gtp-binding protein rho8,rnd3. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: sfn, hme1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606

Resolution:

1.90Å R-factor: 0.154 R-free: 0.200

Authors:

F.Centorrino,B.Andlovic,C.Ottmann

Key ref:

B.Andlovic et al. Inf alpha primes ovarian cancer cells for fusicoccin- Cell death via stabilization of 14-3-3 protein-Protei interactions. To be published, . PubMed id: 37130519

Date:

21-Apr-21 Release date: 04-May-22

Protein chain

P31947  (1433S_HUMAN) -  14-3-3 protein sigma from Homo sapiens

Seq: 248 a.a.

Struc: 236 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)