PDBsum entry 7nma

Signaling protein

PDB id: 7nma

Contents

Protein chain

233 a.a.

Ligands

VAL-ARG-SER-LEU-SEP-GLU-ARG-LEU

Metals

_MG

_CL

Waters ×344

PDB id:

7nma

Name:

Signaling protein

Title:

Crystal structure of 14-3-3 sigma in complex with 13mer amot-p130 peptide

Structure:

14-3-3 protein sigma. Chain: a. Synonym: epithelial cell marker protein 1,stratifin. Engineered: yes. Amot-p130 phosphopeptide (ps175). Chain: p. Synonym: angiomotin. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: sfn, hme1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606

Resolution:

1.75Å R-factor: 0.172 R-free: 0.220

Authors:

F.Centorrino,C.Ottmann

Key ref:

F.Centorrino et al. Fragment-Based exploration of the 14-3-3/amot-P130 in. Curr res struct biol, . PubMed id: 35036934

Date:

23-Feb-21 Release date: 12-Jan-22

Protein chain

P31947  (1433S_HUMAN) -  14-3-3 protein sigma from Homo sapiens

Seq: 248 a.a.

Struc: 233 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)