PDBsum entry 7n5c

Immune system

PDB id: 7n5c

Contents

Protein chains

274 a.a.

100 a.a.

194 a.a.

240 a.a.

Ligands

SER-SER-LEU-CYS-ASN-PHE-ARG-ALA-TYR-VAL

Metals

_NA

Waters ×261

PDB id:

7n5c

Name:

Immune system

Title:

6218 tcr in complex with h2db pa with an engineered tcr-pmhc disulfide bond

Structure:

H-2 class i histocompatibility antigen, d-b alpha chain. Chain: a. Synonym: h-2d(b). Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. Peptide from polymerase acidic protein. Chain: c.

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: h2-d1. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768. Homo sapiens. Human. Organism_taxid: 9606.

Resolution:

1.87Å R-factor: 0.206 R-free: 0.233

Authors:

C.Szeto,S.Gras

Key ref:

C.Szeto and s.gras 6218 tcr in complex with h2db pa with an engineered t disulfide bond. To be published, . PubMed id: 35999236

Date:

05-Jun-21 Release date: 20-Jul-22

Protein chain

P01899  (HA11_MOUSE) -  H-2 class I histocompatibility antigen, D-B alpha chain from Mus musculus

Seq: 362 a.a.

Struc: 274 a.a.*

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

Protein chain

A0A075B6C4  (A0A075B6C4_MOUSE) -  T cell receptor alpha variable 21-DV12 (Fragment) from Mus musculus

Seq: 109 a.a.

Struc: 194 a.a.*

Protein chain

K7N5N2  (K7N5N2_HUMAN) -  T-cell receptor, sp3.4 alpha chain from Homo sapiens

Seq: 207 a.a.

Struc: 194 a.a.*

Protein chain

A0A0G2LB96  (A0A0G2LB96_MOUSE) -  T cell receptor beta, variable 29 (Fragment) from Mus musculus

Seq: 114 a.a.

Struc: 240 a.a.*

Protein chain

K7N5M4  (K7N5M4_HUMAN) -  Human nkt tcr beta chain from Homo sapiens

Seq: 259 a.a.

Struc: 240 a.a.*

* PDB and UniProt seqs differ at 89 residue positions (black crosses)