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PDBsum entry 7n1f

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protein ligands Protein-protein interface(s) links
Immune system PDB id
7n1f

 

 

 

 

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Contents
Protein chains
197 a.a.
240 a.a.
272 a.a.
100 a.a.
Ligands
TYR-LEU-GLN-PRO-
ARG-THR-PHE-LEU-
LEU
Waters ×87
PDB id:
7n1f
Name: Immune system
Title: Sars-cov-2 ylq peptide-specific tcr pylq7 binds to ylq-hla-a2
Structure: Pylq7 t cell receptor alpha chain. Chain: d. Engineered: yes. Pylq7 t cell receptor beta chain. Chain: e. Engineered: yes. Mhc class i antigen, a-2 alpha chain. Chain: a. Engineered: yes.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tcr alpha. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: tcr beta. Gene: hla-a. Gene: b2m, cdabp0092, hdcma22p.
Resolution:
2.39Å     R-factor:   0.199     R-free:   0.236
Authors: D.Wu,R.A.Mariuzza
Key ref: D.Wu et al. (2022). Structural assessment of hla-A2-Restricted sars-Cov-2 epitopes recognized by public and private t-Cell rece. Nat commun, 13, 19. PubMed id: 35013235
Date:
27-May-21     Release date:   28-Jul-21    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 197 a.a.
Protein chain
No UniProt id for this chain
Struc: 240 a.a.
Protein chain
Pfam   ArchSchema ?
A0A5B8RNS7  (A0A5B8RNS7_HUMAN) -  MHC class I antigen (Fragment) from Homo sapiens
Seq:
Struc:
337 a.a.
272 a.a.
Protein chain
Pfam   ArchSchema ?
P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens
Seq:
Struc:
119 a.a.
100 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

 

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