PDBsum entry 7n1b

Immune system

PDB id: 7n1b

Contents

Protein chains

274 a.a.

100 a.a.

Ligands

ARG-LEU-GLN-SER-LEU-GLN-THR-TYR-VAL ×2

PDB id:

7n1b

Name:

Immune system

Title:

Sars-cov-2 rlq peptide binds to hla-a2

Structure:

Mhc class i antigen, a-2 alpha chain. Chain: a, d. Engineered: yes. Beta-2-microglobulin. Chain: b, e. Fragment: unp residues 21-119. Engineered: yes. Spike protein s2. Chain: c, f.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Severe acute respiratory syndrome coronavirus

Resolution:

2.81Å R-factor: 0.214 R-free: 0.269

Authors:

D.Wu,R.A.Mariuzza

Key ref:

D.Wu et al. Structural basis for recognition of two hla-A2-Restri sars-Cov-2 spike epitopes by public and private t cel receptors. Biorxiv, . PubMed id: 35013235

Date:

27-May-21 Release date: 28-Jul-21

Protein chains

A0A140T913  (A0A140T913_HUMAN) -  Major histocompatibility complex, class I, A from Homo sapiens

Seq: 371 a.a.

Struc: 274 a.a.

Protein chains

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)