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PDBsum entry 7n1a
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protein ligands Protein-protein interface(s) links
Immune system PDB id
7n1a

 

 

 

 

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Contents
Protein chains
275 a.a.
100 a.a.
Ligands
TYR-LEU-GLN-PRO-
ARG-THR-PHE-LEU-
LEU ×2
PG4 ×2
Waters ×482
PDB id:
7n1a
Name: Immune system
Title: Sars-cov-2 ylq peptide binds to hla-a2
Structure: Mhc class i antigen, a-2 alpha chain. Chain: a, d. Engineered: yes. Beta-2-microglobulin. Chain: b, e. Fragment: unp residues 21-119. Engineered: yes. Spike protein s1. Chain: c, f.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Severe acute respiratory syndrome coronavirus
Resolution:
2.07Å     R-factor:   0.199     R-free:   0.241
Authors: D.Wu,R.A.Mariuzza
Key ref: D.Wu et al. (2022). Structural assessment of hla-A2-Restricted sars-Cov-2 epitopes recognized by public and private t-Cell rece. Nat commun, 13, 19. PubMed id: 35013235
Date:
27-May-21     Release date:   28-Jul-21    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
A0A140T913  (A0A140T913_HUMAN) -  Major histocompatibility complex, class I, A from Homo sapiens
Seq:
Struc: 		371 a.a.
275 a.a.
Protein chains
Pfam   ArchSchema ?
P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens
Seq:
Struc: 		119 a.a.
100 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 1 residue position (black cross)

 

 

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