PDBsum entry 7mw3

Viral protein/immune system

PDB id: 7mw3

Contents

Protein chains

215 a.a.

212 a.a.

1004 a.a.

Ligands

NAG-NAG ×21

NAG ×30

PDB id:

7mw3

Name:

Viral protein/immune system

Title:

Structure of the sars-cov-2 spike trimer with two rbds down in complex with the fab fragment of human neutralizing antibody clone 6

Structure:

Fab of antibody clone 6, light chain. Chain: l, g, e. Engineered: yes. Fab of antibody clone 6, heavy chain. Chain: h, f, d. Engineered: yes. Spike glycoprotein. Chain: c, b, a. Synonym: s glycoprotein, e2, peplomer protein.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Severe acute respiratory syndrome coronavirus 2. Organism_taxid: 2697049. Gene: s, 2.

Authors:

Y.Hu,Y.Xiong

Key ref:

Y.Hu and y.xiong Development, Structure and function of potent monospe and bispecific monoclonal antibodies that neutralize sars-Cov-2 and its mutant variant. To be published, . PubMed id: 35347138

Date:

15-May-21 Release date: 16-Mar-22

Protein chains

No UniProt id for this chain

Struc: 215 a.a.

Protein chains

No UniProt id for this chain

Struc: 212 a.a.

Protein chains

P0DTC2  (SPIKE_SARS2) -  Spike glycoprotein from Severe acute respiratory syndrome coronavirus 2

Seq: 1273 a.a.

Struc: 1004 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)