PDBsum entry 7mkb

Immune system/viral protein

PDB id: 7mkb

Contents

Protein chains

274 a.a.

100 a.a.

Ligands

TYR-LEU-GLN-PRO-ARG-THR-PHE-LEU-LEU

GOL ×4

Waters ×339

PDB id:

7mkb

Name:

Immune system/viral protein

Title:

Human leukocyte antigen a 0201 In complex with sars-cov-2 epitope ylqprtfll

Structure:

Mhc class i antigen. Chain: a. Fragment: unp residues 25-298. Engineered: yes. Beta-2-microglobulin. Chain: b. Fragment: unp residues 21-119. Engineered: yes. Spike protein s1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-a. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: b2m, cdabp0092, hdcma22p. Synthetic: yes. Severe acute respiratory syndrome coronavirus

Resolution:

1.90Å R-factor: 0.166 R-free: 0.209

Authors:

S.T.Nyovanie,Y.Patskovsky,M.Krogsgaard

Key ref:

S.T.Nyovanie et al. Human leukocyte antigen a0201 In complex with sars-C epitope ylqprtfll. To be published, .

Date:

22-Apr-21 Release date: 26-May-21

Protein chain

A0A140T913  (A0A140T913_HUMAN) -  Major histocompatibility complex, class I, A from Homo sapiens

Seq: 371 a.a.

Struc: 274 a.a.

Protein chain

P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens

Seq: 119 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)