PDBsum entry 7lyh

Viral protein/inhibitor

PDB id: 7lyh

Contents

Protein chain

304 a.a.

Ligands

YHJ

GOL ×2

Waters ×197

PDB id:

7lyh

Name:

Viral protein/inhibitor

Title:

Crystal structure of the sars-cov-2 (covid-19) main protease in complex with inhibitor uawj9-36-1

Structure:

3c-like proteinase. Chain: a. Synonym: 3cl-pro, 3clp, main protease, mpro1, non-structural protein 5, nsp5, sars coronavirus main proteinase. Engineered: yes

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov, sars-cov-2, covid-19 virus. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768

Resolution:

1.90Å R-factor: 0.182 R-free: 0.222

Authors:

M.Sacco,J.Wang,Y.Chen

Key ref:

M.Sacco Crystal structure of the sars-Cov-2 (covid-19) main p in complex with inhibitor uawj9-36-1. To be published, . PubMed id: 34414360

Date:

07-Mar-21 Release date: 17-Mar-21

Protein chain

P0DTD1  (R1AB_SARS2) -

Enzyme reactions

• Enzyme class: E.C.3.4.22.69 - Sars coronavirus main proteinase.