 |
PDBsum entry 7lx9
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Protein binding,hydrolase
|
PDB id
|
|
|
|
7lx9
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Protein binding,hydrolase
|
|
|
Title:
|
|
T4 lysozyme mutant l99a
|
|
Structure:
|
|
Lysozyme. Chain: a. Synonym: lysis protein,endolysin,muramidase. Engineered: yes. Mutation: yes
|
|
Source:
|
|
Enterobacteria phage t4. Bacteriophage t4. Organism_taxid: 10665. Gene: e, t4tp126. Expressed in: escherichia coli 'bl21-gold(de3)plyss ag'. Expression_system_taxid: 866768
|
|
Resolution:
|
|
|
1.19Å
|
R-factor:
|
0.215
|
R-free:
|
0.223
|
|
|
Authors:
|
|
A.S.Kamenik,I.Singh,P.Lak,T.E.Balius,K.R.Liedl,B.K.Shoichet
|
|
Key ref:
|
|
A.S.Kamenik
et al.
Ligand discovery to find the key to opening: testing molecular dynamics based energy penalties for flexibl receptor docking.
To be published,
.
PubMed id:
|
|
|
Date:
|
|
|
03-Mar-21
|
Release date:
|
19-May-21
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
P00720
(ENLYS_BPT4) -
Endolysin from Enterobacteria phage T4
|
|
|
|
Seq:
Struc:
|
|
|
|
164 a.a.
160 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
|
*
PDB and UniProt seqs differ
at 3 residue positions (black
crosses)
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.3.2.1.17
- lysozyme.
|
|
|
|
|
|
|
Reaction:
|
|
Hydrolysis of the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of the prokaryotes cell walls.
|
|
|
|
|
|
|
|
Links
