PDBsum entry 7l6t

Viral protein/RNA

PDB id

7l6t

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Contents

			Protein chains

					299 a.a.


					114 a.a.

			DNA/RNA

			Ligands

					FMT


					SAH


					GLC ×2


					BDF

			Metals

					_MG ×2


					_CL


					_ZN ×2

			Waters ×531

PDB id:

7l6t

Links

Name:

Viral protein/RNA

Title:

Crystal structure of sars-cov-2 nsp16/10 heterodimer in complex with (m7gpppa2m)pupupapapa (cap-1), s-adenosyl-l-homocysteine (sah) and two magnesium (mg) ions.

Structure:

2'-o-methyltransferase. Chain: a. Synonym: nsp16. Engineered: yes. Non-structural protein 10. Chain: b. Synonym: nsp10. Engineered: yes. RNA (5'-d( (M7g))-r(p (A2m)p Up Up A)-3').

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov,sars-cov-2. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: magic. Synthetic: yes.

Resolution:

1.78Å

R-factor:

0.142

R-free:

0.162

Authors:

G.Minasov,L.Shuvalova,M.Rosas-Lemus,O.Kiryukhina,J.S.Brunzelle, K.J.F.Satchell,Center For Structural Genomics Of Infectious Diseases (Csgid)

Key ref:

G.Minasov et al. Crystal structure of sars-Cov-2 nsp16/10 heterodimer complex with (m7gpppa2m)pupupapapa (cap-1), S-Adenosyl-L-Homocysteine (sah) and two magnesium (mg. To be published, . PubMed id: 34131072

Date:

23-Dec-20

Release date:

06-Jan-21

PROCHECK