PDBsum entry 7kyu

Hydrolase/hydrolase inhibitor

PDB id: 7kyu

Contents

Protein chain

302 a.a.

Ligands

XC4

EDO

Waters ×201

PDB id:

7kyu

Name:

Hydrolase/hydrolase inhibitor

Title:

The crystal structure of sars-cov-2 main protease with the formation of cys145-1h-indole-5-carboxylate

Structure:

3c-like proteinase. Chain: a. Engineered: yes

Source:

Severe acute respiratory syndrome coronavirus 2. 2019-ncov. Organism_taxid: 2697049. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.48Å R-factor: 0.162 R-free: 0.187

Authors:

K.Tan,N.I.Maltseva,R.P.Jedrzejczak,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

Key ref:

K.Tan et al. The crystal structure of sars-Cov-2 main protease wit formation of cys145-1h-Indole-5-Carboxylate. To be published, .

Date:

08-Dec-20 Release date: 16-Dec-20

Protein chain

P0DTD1  (R1AB_SARS2) -

Enzyme reactions

• Enzyme class: E.C.3.4.22.69 - Sars coronavirus main proteinase.