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PDBsum entry 7kpf
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Contents |
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152 a.a.
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142 a.a.
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135 a.a.
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PDB id:
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Transferase
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Title:
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Nme2 bound to myristoyl-coa
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Structure:
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Nucleoside diphosphate kinase b. Chain: a, b, c, d, e, f. Synonym: ndp kinase b,c-myc purine-binding transcription factor puf, histidine protein kinase ndkb,nm23-h2. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: nme2, nm23b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008
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Resolution:
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2.23Å
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R-factor:
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0.190
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R-free:
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0.229
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Authors:
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I.R.Price,H.Lin
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Key ref:
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S.Zhang
et al.
A chemical proteomic approach reveals the regulation nme1/2 and cancer metastasis by long-Chain fatty acyl coenzyme a.
To be published,
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Date:
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11-Nov-20
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Release date:
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02-Feb-22
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PROCHECK
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Headers
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References
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P22392
(NDKB_HUMAN) -
Nucleoside diphosphate kinase B from Homo sapiens
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Seq:
Struc:
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152 a.a.
152 a.a.
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Enzyme class 2:
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Chains A, B, C, D, E, F:
E.C.2.7.13.3
- histidine kinase.
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Reaction:
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ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
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ATP
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+
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protein L-histidine
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=
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ADP
Bound ligand (Het Group name = )
matches with 81.82% similarity
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+
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protein N-phospho-L-histidine
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Enzyme class 3:
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Chains A, B, C, D, E, F:
E.C.2.7.4.6
- nucleoside-diphosphate kinase.
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Reaction:
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1.
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a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP
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2.
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a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP
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ribonucleoside 5'-diphosphate
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+
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ATP
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=
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ribonucleoside 5'-triphosphate
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+
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ADP
Bound ligand (Het Group name = )
matches with 81.82% similarity
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2'-deoxyribonucleoside 5'-diphosphate
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+
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ATP
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=
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2'-deoxyribonucleoside 5'-triphosphate
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+
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ADP
Bound ligand (Het Group name = )
matches with 81.82% similarity
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
