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PDBsum entry 7jsr
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Oxidoreductase
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PDB id
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7jsr
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PDB id:
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| Name: |
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Oxidoreductase
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Title:
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Crystal structure of the large glutamate dehydrogenase composed of 180 kda subunits from mycobacterium smegmatis
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Structure:
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NAD-specific glutamate dehydrogenase. Chain: a, b. Synonym: NAD-gdh,NAD(+)-dependent glutamate dehydrogenase. Engineered: yes
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Source:
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Mycolicibacterium smegmatis. Organism_taxid: 246196. Strain: atcc 700084 / mc(2)155, mc2 155. Gene: gdh, msmeg_4699, msmei_4582. Expressed in: escherichia coli b. Expression_system_taxid: 37762
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Resolution:
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6.27Å
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R-factor:
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0.229
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R-free:
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0.284
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Authors:
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M.Lazaro,R.Melero,C.Huet,J.P.Lopez-Alonso,S.Delgado,A.Dodu,E.M.Bruch, L.A.Abriata,P.M.Alzari,M.Valle,M.N.Lisa
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Key ref:
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M.Lazaro
et al.
(2021).
3d architecture and structural flexibility revealed i subfamily of large glutamate dehydrogenases by a mycobacterial enzyme.
Commun biol,
4,
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PubMed id:
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Date:
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15-Aug-20
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Release date:
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09-Jun-21
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PROCHECK
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Headers
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References
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A0R1C2
(DHE2_MYCS2) -
NAD-specific glutamate dehydrogenase from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
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Seq:
Struc:
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1594 a.a.
1554 a.a.
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Enzyme class:
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E.C.1.4.1.2
- glutamate dehydrogenase.
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Reaction:
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L-glutamate + NAD+ + H2O = 2-oxoglutarate + NH4+ + NADH + H+
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L-glutamate
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+
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NAD(+)
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+
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H2O
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=
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2-oxoglutarate
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+
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NH4(+)
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+
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NADH
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
