PDBsum entry 7jpr

Replication

PDB id: 7jpr

Contents

Protein chains

352 a.a.

307 a.a.

593 a.a.

406 a.a.

387 a.a.

Ligands

ATP ×3

Metals

_MG ×3

PDB id:

7jpr

Name:

Replication

Title:

Orc-open: human origin recognition complex (orc) in an open conformation

Structure:

Origin recognition complex subunit 1. Chain: a. Synonym: replication control protein 1. Engineered: yes. Origin recognition complex subunit 2. Chain: b. Engineered: yes. Origin recognition complex subunit 3. Chain: c.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: orc1, orc1l, parc1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: orc2, orc2l. Gene: orc3, latheo, orc3l. Gene: orc4, orc4l.

Authors:

M.J.Jaremko,L.Joshua-Tor

Key ref:

M.J.Jaremko et al. (2020). The dynamic nature of the human origin recognition co revealed through five cryoem structures.. Elife, 9, . PubMed id: 32808929

Date:

09-Aug-20 Release date: 09-Sep-20

Protein chain

Q13415  (ORC1_HUMAN) -  Origin recognition complex subunit 1 from Homo sapiens

Seq: 861 a.a.

Struc: 352 a.a.

Protein chain

Q13416  (ORC2_HUMAN) -  Origin recognition complex subunit 2 from Homo sapiens

Seq: 577 a.a.

Struc: 307 a.a.

Protein chain

Q9UBD5  (ORC3_HUMAN) -  Origin recognition complex subunit 3 from Homo sapiens

Seq: 711 a.a.

Struc: 593 a.a.

Protein chain

O43929  (ORC4_HUMAN) -  Origin recognition complex subunit 4 from Homo sapiens

Seq: 436 a.a.

Struc: 406 a.a.

Protein chain

O43913  (ORC5_HUMAN) -  Origin recognition complex subunit 5 from Homo sapiens

Seq: 435 a.a.

Struc: 387 a.a.