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PDBsum entry 7g21

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protein ligands metals links
Lipid binding protein PDB id
7g21

 

 

 

 

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Contents
Protein chain
134 a.a.
Ligands
FMT
SO4
IKQ
Metals
_CL
Waters ×191
PDB id:
7g21
Name: Lipid binding protein
Title: Crystal structure of human fabp4 in complex with 4-hydroxy-2-[(e)-2- (2-phenylcyclohexyl)ethenyl]-2,3-dihydropyran-6-one, i.E. Smiles [c@h]1([c@@h](/c=c/[c@h]2cc(=cc(=o)o2)o)cccc1)c1ccccc1 with ic50=0.065 microm
Structure: Fatty acid-binding protein, adipocyte. Chain: a. Synonym: adipocyte lipid-binding protein,albp,adipocyte-type fatty acid-binding protein,a-fabp,afabp,fatty acid-binding protein 4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fabp4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
1.12Å     R-factor:   0.149     R-free:   0.182
Authors: A.Ehler,J.Benz,U.Obst,M.Boehringer,M.G.Rudolph
Key ref: U.Obst et al. Crystal structure of a human fabp4 complex. To be published, . PubMed id: 40748031
Date:
04-May-23     Release date:   14-Jun-23    
PROCHECK
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 Headers
 References

Protein chain
P15090  (FABP4_HUMAN) -  Fatty acid-binding protein, adipocyte from Homo sapiens
Seq:
Struc:
132 a.a.
134 a.a.
Key:    Secondary structure

 

 

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