PDBsum entry 7g0m

Lipid binding protein

PDB id: 7g0m

Contents

Protein chain

134 a.a.

Ligands

WKR

FMT

SO4 ×2

Waters ×189

PDB id:

7g0m

Name:

Lipid binding protein

Title:

Crystal structure of human fabp4 in complex with 2-tert-butylsulfanyl- 6-phenyl-1h-1,3,5-triazine-4-thione, i.E. Smiles c1(=nc(=s)n=c(n1) sc(c)(c)c)c1ccccc1 with ic50=8.7 microm

Structure:

Fatty acid-binding protein, adipocyte. Chain: a. Synonym: adipocyte lipid-binding protein,albp,adipocyte-type fatty acid-binding protein,a-fabp,afabp,fatty acid-binding protein 4. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fabp4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.05Å R-factor: 0.148 R-free: 0.176

Authors:

A.Ehler,J.Benz,U.Obst,M.Boehringer,M.G.Rudolph

Key ref:

U.Obst et al. Crystal structure of a human fabp4 complex. To be published, . PubMed id: 40748031

Date:

27-Apr-23 Release date: 14-Jun-23

Protein chain

P15090  (FABP4_HUMAN) -  Fatty acid-binding protein, adipocyte from Homo sapiens

Seq: 132 a.a.

Struc: 134 a.a.