PDBsum entry 7fyc

Lipid binding protein

PDB id: 7fyc

Contents

Protein chain

133 a.a.

Ligands

SO4 ×2

VJ3

Waters ×199

PDB id:

7fyc

Name:

Lipid binding protein

Title:

Crystal structure of human fabp4 in complex with (2r)-1-[(2- phenylphenyl)carbamoyl]pyrrolidine-2-carboxylic acid, i.E. Smiles c1[c@@h](n(cc1)c(=o)nc1ccccc1c1ccccc1)c(=o)o with ic50=0.466 microm

Structure:

Fatty acid-binding protein, adipocyte. Chain: a. Synonym: adipocyte lipid-binding protein,albp,adipocyte-type fatty acid-binding protein,a-fabp,afabp,fatty acid-binding protein 4. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fabp4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.08Å R-factor: 0.151 R-free: 0.182

Authors:

A.Ehler,J.Benz,U.Obst,U.Obst-Sander,M.G.Rudolph

Key ref:

U.Obst et al. Crystal structure of a human fabp4 complex. To be published, . PubMed id: 40748031

Date:

27-Apr-23 Release date: 14-Jun-23

Protein chain

P15090  (FABP4_HUMAN) -  Fatty acid-binding protein, adipocyte from Homo sapiens

Seq: 132 a.a.

Struc: 133 a.a.