PDBsum entry 7fxc

Lipid binding protein

PDB id: 7fxc

Contents

Protein chain

133 a.a.

Ligands

SO4 ×2

R80

Waters ×219

PDB id:

7fxc

Name:

Lipid binding protein

Title:

Crystal structure of human fabp4 in complex with 6-[(3,4- dichlorophenyl)methyl]-5-methyl-1,1-dioxo-1,2,6-thiadiazin-3-one, i.E. Smiles n1(cc2cc(c(cc2)cl)cl)s(=o)(=o)nc(=o)c=c1c with ic50=0.945 microm

Structure:

Fatty acid-binding protein, adipocyte. Chain: a. Synonym: adipocyte lipid-binding protein,albp,adipocyte-type fatty acid-binding protein,a-fabp,afabp,fatty acid-binding protein 4. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fabp4. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.12Å R-factor: 0.136 R-free: 0.153

Authors:

A.Ehler,J.Benz,U.Obst,A.Albrecht-Harry,M.G.Rudolph

Key ref:

U.Obst et al. Crystal structure of a human fabp4 complex. To be published, . PubMed id: 40748031

Date:

27-Apr-23 Release date: 14-Jun-23

Protein chain

P15090  (FABP4_HUMAN) -  Fatty acid-binding protein, adipocyte from Homo sapiens

Seq: 132 a.a.

Struc: 133 a.a.