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PDBsum entry 7fcc

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protein links
Immune system PDB id
7fcc

 

 

 

 

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Contents
Protein chain
146 a.a.
Waters ×54
PDB id:
7fcc
Name: Immune system
Title: Il-1racpb tir domain
Structure: Isoform 4 of interleukin-1 receptor accessory protein. Chain: a. Synonym: il-1 receptor accessory protein. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: il1rap, c3orf13, il1r3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
2.14Å     R-factor:   0.202     R-free:   0.243
Authors: X.Wang,J.Zhou
Key ref: X.Wang and j.zhou The crystal structure of il-1racpb tir domain at 2.14 angstroms resolution.. To be published, .
Date:
14-Jul-21     Release date:   20-Jul-22    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q9NPH3  (IL1AP_HUMAN) -  Interleukin-1 receptor accessory protein from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
570 a.a.
146 a.a.*
Key:    PfamA domain  Secondary structure
* PDB and UniProt seqs differ at 64 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.2.2.6  - ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: NAD+ + H2O = ADP-D-ribose + nicotinamide + H+
NAD(+)
+ H2O
= ADP-D-ribose
+ nicotinamide
+ H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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