PDBsum entry 7f5c

Antitumor protein

PDB id: 7f5c

Contents

Protein chain

108 a.a.

Ligands

EUU

Waters ×132

PDB id:

7f5c

Name:

Antitumor protein

Title:

Crystal structure of bptf-brd with ligand dc-bpi-07 bound

Structure:

Nucleosome-remodeling factor subunit bptf. Chain: a. Fragment: bromodomain phd. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: bptf. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.65Å R-factor: 0.185 R-free: 0.217

Authors:

T.Lu,H.B.Lu,J.Wang,H.Lin,W.Lu,C.Luo

Key ref:

T.Lu et al. Discovery and optimization of small-Molecule inhibito the bptf bromodomains proteins. To be published, .

Date:

21-Jun-21 Release date: 29-Jun-22

Protein chain

J3QQQ8  (J3QQQ8_HUMAN) -  Bromodomain PHD finger transcription factor (Fragment) from Homo sapiens

Seq: 420 a.a.

Struc: 108 a.a.

Enzyme reactions

• Enzyme class: E.C.?