PDBsum entry 7f0c

Transferase

PDB id: 7f0c

Contents

Protein chain

282 a.a.

Ligands

KBE-DPP-UAL-MYN-DPP-SER

Waters ×131

PDB id:

7f0c

Name:

Transferase

Title:

Crystal structure of capreomycin phosphotransferase in complex with cmn iia

Structure:

Capreomycin phosphotransferase. Chain: a. Engineered: yes. Dpp-ser-dpp-ual-myn-kbe. Chain: c. Engineered: yes

Source:

Saccharothrix mutabilis subsp. Capreolus. Streptomyces capreolus. Organism_taxid: 66854. Gene: cph. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562

Resolution:

2.07Å R-factor: 0.219 R-free: 0.254

Authors:

C.Y.Chang,Y.C.Pan,Y.L.Wang,S.I.Toh

Key ref:

Y.C.Pan et al. (2022). Dual-Mechanism confers self-Resistance to the antituberculosis antibiotic capreomycin.. Acs chem biol, 17, 138. PubMed id: 34994196

Date:

03-Jun-21 Release date: 11-May-22

Protein chain

Q53826  (Q53826_STRMP) -  Capreomycin phosphotransferase from Saccharothrix mutabilis subsp. capreolus

Seq: 281 a.a.

Struc: 282 a.a.