PDBsum entry 7et3

Viral protein

PDB id: 7et3

Contents

Protein chains

285 a.a.

20 a.a.

237 a.a.

290 a.a.

468 a.a.

65 a.a.

69 a.a.

285 a.a.

63 a.a.

(+ 0 more) 1286 a.a.

PDB id:

7et3

Name:

Viral protein

Title:

C5 portal vertex in the enveloped virion capsid

Structure:

Triplex capsid protein 2. Chain: h, i, n, o. Large tegument protein deneddylase. Chain: h, p. Synonym: ul48. Triplex capsid protein 1. Chain: g, m. Capsid vertex component 1. Chain: m.

Source:

Human cytomegalovirus. Hhv-5, human herpesvirus 5. Organism_taxid: 10359. Organism_taxid: 10359

Authors:

Z.Li,X.Yu

Key ref:

Z.Li et al. (2021). Structural basis for genome packaging, Retention, And ejection in human cytomegalovirus.. Nat commun, 12, 4538. PubMed id: 34315863

Date:

12-May-21 Release date: 14-Jul-21

Protein chains

P16728  (TRX2_HCMVA) -  Triplex capsid protein 2 from Human cytomegalovirus (strain AD169)

Seq: 306 a.a.

Struc: 285 a.a.

Protein chains

P16785  (LTP_HCMVA) -  Large tegument protein deneddylase from Human cytomegalovirus (strain AD169)

Seq: 2241 a.a.

Struc: 20 a.a.

Protein chain

P16783  (TRX1_HCMVA) -  Triplex capsid protein 1 from Human cytomegalovirus (strain AD169)

Seq: 290 a.a.

Struc: 237 a.a.

Protein chain

P16783  (TRX1_HCMVA) -  Triplex capsid protein 1 from Human cytomegalovirus (strain AD169)

Seq: 290 a.a.

Struc: 290 a.a.

Protein chain

P16799  (CVC1_HCMVA) -  Capsid vertex component 1 from Human cytomegalovirus (strain AD169)

Seq: 594 a.a.

Struc: 468 a.a.

Protein chain

P16726  (CVC2_HCMVA) -  Capsid vertex component 2 from Human cytomegalovirus (strain AD169)

Seq: 642 a.a.

Struc: 65 a.a.

Protein chain

P16726  (CVC2_HCMVA) -  Capsid vertex component 2 from Human cytomegalovirus (strain AD169)

Seq: 642 a.a.

Struc: 69 a.a.

Protein chain

P08318  (PP150_HCMVA) -  Large structural phosphoprotein from Human cytomegalovirus (strain AD169)

Seq: 1048 a.a.

Struc: 285 a.a.

Protein chains

Q7M6N6  (SCP_HCMVA) -  Small capsomere-interacting protein from Human cytomegalovirus (strain AD169)

Seq: 75 a.a.

Struc: 63 a.a.

Protein chains

P16729  (MCP_HCMVA) -  Major capsid protein from Human cytomegalovirus (strain AD169)

Seq: 1370 a.a.

Struc: 1286 a.a.

Enzyme reactions

• Enzyme class 1: Chains H, P: E.C.3.4.19.12 - ubiquitinyl hydrolase 1.
• Reaction: Thiol-dependent hydrolysis of ester, thiolester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
• Enzyme class 2: Chains H, P: E.C.3.4.22.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.