PDBsum entry 7el4

Oncoprotein

PDB id: 7el4

Contents

Protein chain

94 a.a.

Ligands

O4B ×2

Metals

_MG ×2

Waters ×36

PDB id:

7el4

Name:

Oncoprotein

Title:

The crystal structure of p53p peptide fragment in complex with the n- terminal domain of mdmx

Structure:

Cellular tumor antigen p53,protein mdm4. Chain: a. Synonym: double minute 4 protein,mdm2-like p53-binding protein, protein mdmx,p53-binding protein mdm4. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: mdm4, mdmx. Expressed in: escherichia coli k-12. Expression_system_taxid: 83333.

Resolution:

2.11Å R-factor: 0.224 R-free: 0.225

Authors:

X.Y.Cheng,B.L.Zhang,Z.C.Li,Z.K.Kuang,Z.D.Su

Key ref:

X.Y.Cheng et al. The crystal structure of the n-Terminal domain of mdm complex with p53p peptide fragment. To be published, .

Date:

08-Apr-21 Release date: 09-Jun-21

Protein chain

O15151  (MDM4_HUMAN) -  Protein Mdm4 from Homo sapiens

Seq: 490 a.a.

Struc: 94 a.a.*

Protein chain

P04637  (P53_HUMAN) -  Cellular tumor antigen p53 from Homo sapiens

Seq: 393 a.a.

Struc: 94 a.a.*

* PDB and UniProt seqs differ at 95 residue positions (black crosses)