PDBsum entry 7e9h

Membrane protein

PDB id: 7e9h

Contents

Protein chains

766 a.a.

223 a.a.

306 a.a.

19 a.a.

232 a.a.

Ligands

SEP ×2

PDB id:

7e9h

Name:

Membrane protein

Title:

Cryo-em structure of gi-bound metabotropic glutamate receptor mglu4

Structure:

Metabotropic glutamate receptor 4. Chain: r, s. Synonym: mglur4. Engineered: yes. Guanine nucleotide-binding protein g(i) subunit alpha-3. Chain: a. Synonym: g(i) alpha-3. Engineered: yes. Mutation: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: grm4, gprc1d, mglur4. Expressed in: baculovirus expression vector pfastbac1-hm. Expression_system_taxid: 274590. Gene: gnai3. Gene: gnb1. Gene: gng2.

Authors:

S.Lin,S.Han,Q.Zhao,B.Wu

Key ref:

S.Lin et al. Structures of gi-Bound metabotropic glutamate recepto mglu2 and mglu4.. Nature, . PubMed id: 34135510

Date:

04-Mar-21 Release date: 23-Jun-21

Protein chains

Q14833  (GRM4_HUMAN) -  Metabotropic glutamate receptor 4 from Homo sapiens

Seq: 912 a.a.

Struc: 766 a.a.

Protein chain

P08754  (GNAI3_HUMAN) -  Guanine nucleotide-binding protein G(i) subunit alpha-3 from Homo sapiens

Seq: 354 a.a.

Struc: 223 a.a.*

Protein chain

P62873  (GBB1_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 from Homo sapiens

Seq: 340 a.a.

Struc: 306 a.a.

Protein chain

P59768  (GBG2_HUMAN) -  Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 from Homo sapiens

Seq: 71 a.a.

Struc: 19 a.a.

Protein chain

No UniProt id for this chain

Struc: 232 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)